Drug Name:Andexanet Alfa
Drug Class:Antidote
Mechanism of Action:Binds to and sequesters direct and indirect factor Xa inhibitors
Use:
  • Reversal of anticoagulation in patients taking direct or indirect factor Xa inhibitors
  • Emergency surgery or urgent procedures in patients taking factor Xa inhibitors
Side Effects:
  • Nausea
  • Vomiting
  • Peripheral edema
  • Pyrexia
  • Headache
Contraindications:
  • Known hypersensitivity to andexanet alfa or any of its components
Specialty:
  • Hematology
  • Emergency Medicine
  • Critical Care